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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sakurai, Masami | 3B | Saugatuck Joes | 24 | 05/16/2027 | Kakamigahara | JPN | Right | Right | 5' 11" | 185 lbs | - |
| Santos, Raúl | LF | Free Agent | 26 | 04/18/2025 | Detroit | USA | Right | Right | 6' 2" | 200 lbs | - |
| Schaeffer, Ray | RP | Pointe Pelee Monarchs | 34 | 06/01/2017 | Holland | CAN | Right | Right | 6' 2" | 200 lbs | $507,500 |
| Seldon, Jon | C | Pointe Pelee Monarchs | 22 | 06/13/2029 | Walbridge | USA | Right | Right | 6' 0" | 185 lbs | - |
| Sellars, Billy | C | Saugatuck Joes | 29 | 09/18/2021 | Thunder Bay | CAN | Switch | Right | 6' 1" | 200 lbs | $507,500 |
| Sentner, Bradley | RP | Saugatuck Joes | 26 | 01/09/2025 | Mississauga | CAN | Right | Right | 5' 10" | 185 lbs | $507,500 |
| Serrano, Bill | C | Bay City Rollers | 27 | 07/31/2024 | Mississauga | CAN | Switch | Right | 6' 1" | 200 lbs | $770,000 |
| Sharpe, Lee | 1B | Pointe Pelee Monarchs | 27 | 06/02/2024 | Hamilton | CAN | Left | Right | 6' 5" | 215 lbs | $507,500 |
| Si, Song | 3B | Mississauga Mad Catz | 26 | 07/02/2025 | Tanshui | TPE | Right | Right | 6' 1" | 200 lbs | $507,500 |
| Silander, Mark | RP | Free Agent | 23 | 05/31/2028 | Blenheim | CAN | Right | Right | 6' 0" | 180 lbs | - |
| Silva, Gilberto | SP | Pointe Pelee Monarchs | 24 | 04/07/2027 | El Hatillo | VEN | Left | Right | 6' 5" | 200 lbs | - |
| Simmons, Robby | 1B | Free Agent | 31 | 01/18/2020 | Wauwatosa | USA | Left | Left | 6' 4" | 200 lbs | - |
| Simon, Dave | CF | Bay of Quinte Herons | 25 | 06/15/2026 | Chanhassen | USA | Right | Left | 5' 10" | 185 lbs | - |
| Simon, Valentin | RP | Mississauga Mad Catz | 28 | 06/17/2023 | London | CAN | Right | Right | 6' 0" | 190 lbs | - |
| Sonier, Dwain | CF | Plymouth Rockers | 23 | 09/07/2027 | Toronto | CAN | Left | Right | 6' 1" | 195 lbs | - |
| Springer, Xavier | 2B | Free Agent | 29 | 02/14/2022 | Boardman | USA | Right | Right | 5' 9" | 190 lbs | - |
| Stanford, John | LF | Free Agent | 27 | 10/23/2023 | Caledonia | USA | Left | Left | 6' 3" | 200 lbs | - |
| Starr, Darryl | RP | London Eclipse | 31 | 12/07/2019 | Holland | CAN | Right | Right | 6' 2" | 200 lbs | - |
| Stewart, Dan | 1B | Mackinac Island Cougars | 27 | 03/30/2024 | Midland | USA | Right | Right | 5' 9" | 195 lbs | - |
| Stinson, Rick | SP | Bay City Rollers | 23 | 02/22/2028 | Hamilton | CAN | Right | Right | 6' 2" | 170 lbs | - |
| Stott, Bill | RP | London Eclipse | 28 | 05/27/2023 | Oshawa | CAN | Right | Right | 5' 11" | 190 lbs | - |
| Stott, Larry | CL | Saugatuck Joes | 23 | 09/07/2027 | London | CAN | Right | Right | 6' 2" | 200 lbs | $507,500 |
| Stout, Alan | SS | Bay City Rollers | 23 | 06/24/2028 | Fremont | USA | Switch | Right | 6' 2" | 180 lbs | $507,500 |
| Sulis, Gavin | LF | Free Agent | 30 | 08/08/2021 | Nanticoke | CAN | Right | Right | 6' 4" | 220 lbs | - |
| Sullivan, Dave | 2B | Mississauga Mad Catz | 29 | 01/21/2022 | London | CAN | Right | Right | 6' 0" | 195 lbs | $507,500 |
| Sweetland, Flynn | 3B | Bay City Rollers | 24 | 04/11/2027 | Toronto | CAN | Right | Right | 6' 3" | 200 lbs | - |
| Sánchez, Carlos | CF | Leamington Mariners | 27 | 12/17/2023 | Miamisburg | USA | Switch | Right | 6' 0" | 205 lbs | - |
